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Modifications of Titin Contribute to the Progression of Cardiomyopathy and Represent a Therapeutic Target for Treatment of Heart Failure.

J Clin Med · 2020 · PMC7564493 · PMID 32859027

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likely to be significantno p-value reported
Although increasing levels of cGMP is likely to have many effects for improving heart failure, the effects on phosphorylation of the titin N2Bus element is likely to be significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.