It is therefore highly significant that DNMTB3 is recruited to the RASSF1A promoter, leading to hypermethylation and silencing of RASSF1A expression [ 46 ].
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RASSF1A Suppresses Estrogen-Dependent Breast Cancer Cell Growth through Inhibition of the Yes-Associated Protein 1 (YAP1), Inhibition of the Forkhead Box Protein M1 (FOXM1), and Activation of Forkhead Box Transcription Factor 3A (FOXO3A).
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