highly significantP < 2E−16
One interesting example is glycan 5402, which had a small positive correlation (PPMCC 0.28) with A1AT’s serum concentration when present at site A1AT site 70 ( P = 0.006) but had a strong highly significant negative correlation (PPMCC -0.81) with the serum concentration of A1AT when present at A1AT site 271 ( P < 2E−16) (Fig. 2 F).