We observed little if any difference in Tie2 expression between RA and PsA PB-derived macrophages, and only a slight trend towards increased sensitivity to Ang-2 in PsA, indicating that systemic disease influences did not overtly impact on myeloid Tie2 signalling.
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Promotion of macrophage activation by Tie2 in the context of the inflamed synovia of rheumatoid arthritis and psoriatic arthritis patients.
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