Multiscale Model Identifies Improved Schedule for Treatment of Acute Myeloid Leukemia In Vitro With the Mcl-1 Inhibitor AZD5991.

From that initial value, the absolute decline is highly significant and similar for each subsequent cycle, in the range of 0.020–0.024 hour −1 ( P = 6.17 × 10 −7 , 9.74 × 10 −7 , 2.41 × 10 −5 for cycles 2, 3, and 4, respectively).

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