The correlation of HIF-1α expression between the control group (fold change = 0.0954) and the MM group (fold change = 0.622) was at p < 0.0001 as well as differences in the expression at respective disease stages are highly significant (p < 0.0001). 3.2 Analysis of VDR rs2107301 gene polymorphism in blood The observed group of patients with MM was predominantly represented by the homozygous GG group in 53%, followed by the heterozygous AG group in 40% of cases and the least homozygous AA group in 7% of patients with MM.
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Development of novel parameter for monitoring of malignant melanoma progression.
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