Although the assay showed variation in absolute compound binding between biological replicates ( Figure S2 ), we observed an obvious trend: the lectin targeted conjugates reached higher concentrations in the bacterial biofilm than the unmodified ciprofloxacin, independent of their lectin targeting moiety ( Figure 4 ).
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Directing Drugs to Bugs: Antibiotic-Carbohydrate Conjugates Targeting Biofilm-Associated Lectins of <i>Pseudomonas aeruginosa</i>.
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