Exogenous recombinant human insulin-induced severe hypersensitivity reaction precipitating hyperglycemic crisis: A clinical conundrum.

Discussion Type 1 diabetes mellitus has shown an increasing trend since the early 2000s,[ 3 , 4 ] with an annual incidence of 2.8% in 1990–1999,[ 5 ] to about 3.4% in the 2000–2009 period.[ 6 ] The only treatment currently available for it is injectable insulin and can often prove to be a challenging condition to treat in a primary health-care setup because of the frequent fluctuations in blood glucose levels and increased propensity for uncontrolled hyperglycemia to develop into DKA.

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