A high-throughput CRISPR interference screen for dissecting functional regulators of GPCR/cAMP signaling.

PLoS Genet · 2020 · PMC7588078 · PMID 33052901

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hedged sentence

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closest p · 0.0× alpha

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boldest claim

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highly significantp < 1.0x10 -3actually significant

Knockdown of SF3A2 resulted in a much more dramatic upregulation of basal CRE-GFP (~2.5-7-fold increase relative to controls, highly significant for one of the two sgRNAs, p < 1.0x10 -3 by one-way ANOVA test) ( S5A Fig ).

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