Polymorphisms in STING Affect Human Innate Immune Responses to Poxviruses.

Front Immunol · 2020 · PMC7591719 · PMID 33154747

Europe PMC DOI

hedged sentence

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closest p · 0.0× alpha

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boldest claim

The sentences

highly significantp < 1 x 10 −30actually significant

Discussion Our GWAS across two cohorts of smallpox vaccine recipients, totaling just over 1,600 individuals, identified a highly significant (p < 1 x 10 −30 ) association signal from a region on chromosome 5 that was linked to significant inter-individual variations in IFNα response to in vitro stimulation with vaccinia virus.

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