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Differential role of segments of α-mating factor secretion signal in Pichia pastoris towards granulocyte colony-stimulating factor emerging from a wild type or codon optimized copy of the gene.

Microb Cell Fact · 2020 · PMC7597063 · PMID 33121493

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a definite trendno p-value reported
On sequencing eight of the best leader sequences, a definite trend was noticed in that the 22nd Val, in the WT α-MAT, was changed to an Ala.

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