For each of 27,386 highly significant (FDR < 0.001) pairwise inter-omic Spearman correlations calculated in the previous step, we fit a GEE using the model analyte1 ∼age_at_baseline + C(sex) + C(race) + C(ethnicity) + BMI + who_ordinal_scale ∗ analyte2 on the original (non-residualized) data.
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Multi-Omics Resolves a Sharp Disease-State Shift between Mild and Moderate COVID-19.
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