Clinical Outcome and Toxicity in the Treatment of Anaplastic Thyroid Cancer in Elderly Patients.

J Clin Med · 2020 · PMC7600138 · PMID 33050286

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did not achieve significanceno p-value reported

In the multivariate analysis, radiotherapy ( p < 0.001, hazard ratio (HR) = 0.383, 95% confidence interval (CI) = 0.253–0.579) was significantly associated with an improved OS, whereas surgery ( p = 0.107, HR = 0.640, 95% CI = 0.372–1.100), sequential or concurrent chemotherapy ( p = 0.067, HR = 0.664, 95% CI = 0.428–1.029) and multimodal treatment ( p = 0.464, HR = 0.777, 95% CI = 0.396–1.526) did not achieve significance in the multivariate analysis. 3.3.

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failed to achieve significanceno p-value reported

In the multivariate analysis, surgery ( p < 0.001, HR = 0.294, 95% CI = 0.192–0.45), radiotherapy ( p < 0.001, HR = 0.042, 95% CI = 0.018–0.098) and younger age ( p = 0.008, HR = 1.721, 95% CI = 1.151–2.573) were significantly associated with an improved OS, whereas concurrent or sequential chemotherapy ( p = 0.171, HR = 1.406, 95% CI = 0.863–2.289) failed to achieve significance. 3.4.

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