Looking at the ratio of expressions of TGF-β1 and its antagonist BMP7 ( Figure 4 E), the significant increase in female non-diabetic as well as diabetic kidneys versus the corresponding male study groups remains, but there is an additional significant increase in the TGF-β1/BMP7 ratio in female animals under diabetic conditions, which is also reflected in the highly significant sex–diabetes interaction.
1
—
—