A DNA Based Biosensor Amplified With ZIF-8/Ionic Liquid Composite for Determination of Mitoxantrone Anticancer Drug: An Experimental/Docking Investigation.

Front Chem · 2020 · PMC7606923 · PMID 33195033

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a decreasing trendno p-value reported

Analytical Approach Using a decreasing trend in DNA signals and its relationship with the concentration of mitoxantrone, a linear dynamic range from 8.0 nM to 110 μM with the equation of ΔI pa = 0.052 C mitoxantrone + 0.589 ( R 2 = 0.991) and a detection limit of 3.0 nM was calculated to determine mitoxantrone at surface of DNA/BMIMS/ZIF-8/CPE ( Figure 8 ).

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