From 1990 to 2017, the ASIR showed a decreasing trend in most geographical regions except in Central Sub-Saharan Africa and Andean Latin America (Table 1 ).
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Trends in disease burden of chronic myeloid leukemia at the global, regional, and national levels: a population-based epidemiologic study.
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In the past decade, the obesity epidemic has leveled off in developed countries; by contrast, an increasing trend was still evident in developing countries [ 49 , 50 ].