Compromised Humoral Functional Evolution Tracks with SARS-CoV-2 Mortality.

Although there were similar IgA and IgM responses across the two groups, there was an overall trend toward lower IgG3, FcR binding, and Fc functions in the non-survivor,s which were observable by the second week post symptoms but were amplified by week three, similar to what was observed in the univariate analysis ( Figure 1 ).

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