Opioid antagonists are associated with a reduction in the symptoms of schizophrenia: a meta-analysis of controlled trials.

Neuropsychopharmacology · 2020 · PMC7608351 · PMID 32516800

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did not achieve significanceno p-value reported

Analyses of negative scales were severely underpowered ( k = 6 for bootstrap only, random model not assessed) and did not achieve significance, but did have a fairly large average effect size ( g > 0.66).

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