extremely significantp ≤ 0.01
highly significantp ≤ 0.05
p values were designated as follows: **** p < 0.0001 and *** p < 0.001, extremely significant; ** p ≤ 0.01, highly significant; * p ≤ 0.05, significant; and p > 0.05, n.s.
p values were designated as follows: **** p < 0.0001 and *** p < 0.001, extremely significant; ** p ≤ 0.01, highly significant; * p ≤ 0.05, significant; and p > 0.05, n.s.