Does the breakdown of the detoxification system for aldehydes as a result of aldose reductase upregulation lead to alcohol-induced liver injury in humans and mice?

J Diabetes Investig · 2020 · PMC7610110 · PMID 32460409

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highly significantno p-value reported

The observation of this mechanism induced by AR metabolites seems to be highly significant in consideration of a trigger for AR upregulation caused by alcohol.

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