Most notably, comparison of the transcriptional changes induced by HMG20B KD with those observed following LSD1 inhibition in THP1 AML cells with OG86 [ 8 ] revealed a highly significant overlap (Fig. 6D ).
← all excerpts
HMG20B stabilizes association of LSD1 with GFI1 on chromatin to confer transcription repression and leukemia cell differentiation block.
1
—
—