A combination typhoid and non-typhoidal Salmonella polysaccharide conjugate vaccine in healthy adults: a randomized, placebo-controlled phase 1 trial.

Nat Med · 2025 · PMC7618460 · PMID 41062830

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In general, induction of IgG or IgA BM responses to the three polysaccharide antigens observed in D29 samples (from both dosage cohorts), were elevated, either significantly (p<0.05, Figure 4 and Supplementary Table 6 ) or with a positive trend (p<0.1, Figure 4 , panel E ), compared to the corresponding pre-vaccination (D1) levels.

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