Barely Significant
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Rescue therapy with inhaled nitric oxide and almitrine in COVID-19 patients with severe acute respiratory distress syndrome.

Ann Intensive Care · 2020 · PMC7641257 · PMID 33150525

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highly significantno p-value reported
The first reported study on almitrine in severe hypoxia in COVID-19 patients [ 33 ] showed a highly significant increase in P/F ratio with almitrine, independently from the dose used (4 or 12 mcg/kg/min).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.