VWCE Functions as a Tumor Suppressor in Breast Cancer Cells.

Front Oncol · 2020 · PMC7643001 · PMID 33194737

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We found that VWCE-overexpression resulted in a significant downregulation of the mesenchymal markers, vimentin, ZEB1, and ZEB2 in both MDA-MB-231 and MDA-MB-453 cells with the concomitant highly significant upregulation of the epithelial marker, E-cadherin, in both the cell lines ( Figures 4A, B ).

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