A Facile Microwave-Assisted Synthesis of Oxazoles and Diastereoselective Oxazolines Using Aryl-Aldehydes, <i>p</i>-Toluenesulfonylmethyl Isocyanide under Controlled Basic Conditions.

1 Heterocyclic small molecules are enormously significant for studying cell biology and the treatment of diverse diseases as they control the function of enzymes, receptors, and protein–protein interactions. 2 , 3 In this perspective, oxazoles and oxazolines are five-membered heterocyclic moieties containing nitrogen and oxygen as heteroatoms, which established an important class of drug candidates in organic chemistry.

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