Environmental and individual factors associated with protection and predisposition to autoimmune diseases.

When comparing the relative prevalence level of the present study with an Italian study,[ 31 ] it is concluded that the microregion has a lower level probably because its municipalities have low demographic density and low latitude, in addition to the influence of socioeconomic factors advocated by the hygiene theory that argues that prevalence tends to be lower in less developed regions.[ 32 ] Although research has shown an increasing trend in the incidence of rheumatological, endocrinological, gastrointestinal, and neurological ADs worldwide, including in Brazil.[ 33 ] Analyzing the data obtained in Table 2 , it is possible to verify that this study found a higher prevalence of ADs in women, corroborating previous studies that stated

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