marginal significancep = 0.051
Compared to the non-frail group, the frail group had higher MD of the medial frontal cortex, putamen, caudate, thalamus, and anterior cingulate cortex; they also had lower FA of the body of the corpus callosum and superior fronto-occipital fasciculus at a marginal significance ( p = 0.051) after full adjustment ( Table 4 ).