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The Impact of Predialysis Patient Education Counseling on Relative Frequencies of Renal Replacement Modalities.

Cureus · 2020 · PMC7647358 · PMID 33173640

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an increasing trendno p-value reported
An increasing trend in the number of patients with end-stage renal disease (ESRD) has been witnessed worldwide in the past few years, and it is expected to continue for the foreseeable future.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.