Barely Significant
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Metformin changes the immune microenvironment of colorectal cancer in patients with type 2 diabetes mellitus.

Cancer Sci · 2020 · PMC7648042 · PMID 32794612

Europe PMCDOI
1
hedged sentence
0.0510
closest p · 1.0× alpha
0.0510
boldest claim

The sentences

marginally significantP = .051so close (0.05 < p ≤ 0.1)
As shown in Figure 7 , the average fibrotic scores of metformin(+) CRC were lower than those from metformin(–) tumors with a marginally significant difference ( P = .051). 4 DISCUSSION Epidemiological studies suggested that metformin not only reduces the risk of developing CRC but also may improve the outcome of patients with DM and CRC, especially for patients who have undergone curative surgery for stage II and stage III tumors, 25 , 2

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