Barely Significant
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Night Cream Containing Melatonin, Carnosine and Helichrysum italicum Extract Helps Reduce Skin Reactivity and Signs of Photodamage: Ex Vivo and Clinical Studies.

Dermatol Ther (Heidelb) · 2020 · PMC7649196 · PMID 32915393

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The sentences

an overall trendp < 0.05actually significant
Effect on Skin Roughness There was an overall trend towards improvement of skin roughness in the malar region, with Ra (arithmetic mean roughness) reduced by 4.4% at D56 ( p < 0.05) and by 4.2% at D84 ( p < 0.05) (Table 3 ).

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