Next, we determined the expression levels of miR-22 , P16 , PTEN , P21 , and RASSF1A in the xenografts, and the results showed an increasing trend consistent with the in vitro results (Fig. 6g, h ).
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MiR-22, regulated by MeCP2, suppresses gastric cancer cell proliferation by inducing a deficiency in endogenous S-adenosylmethionine.
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