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Drug Discovery and Development of Novel Therapeutics for Inhibiting TMAO in Models of Atherosclerosis and Diabetes.

Front Physiol · 2020 · PMC7658318 · PMID 33192565

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highly significantno p-value reported
These findings are highly significant for development of novel compounds to prevent atherosclerosis in patients with western diets, as non-lethal inhibition promotes reorganization of the gut microbiome without drastically reducing the numbers of beneficial bacteria.

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