Virulence and pathogenesis of SARS-CoV-2 infection in rhesus macaques: A nonhuman primate model of COVID-19 progression.

PLoS Pathog · 2020 · PMC7660522 · PMID 33180882

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a decreasing trendno p-value reported

In contrast, NK cells in PBMC show a decreasing trend from the initial 3 days of infection and do not recovered until 21 dpi.

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an increasing trendno p-value reported

Our results further indicate that CD4+CD25+ CD127- Treg cells show an increasing trend on 5 dpi, confirming their activation during the middle stage of infection, which may lead to immunosuppressive effects consistent with clinical reports[ 25 ].

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