Statistical significance was determined as *p < 0.05 (significant) up to ****p < 0.0001 (highly significant). 3 Results 3.1 Molecular cloning of two chicken IL-18 binding protein isoforms A previous study ( Watanabe et al., 2005 ) identified a truncated chicken expressed sequence tag (Accession: CD727808), which was predicted to contain an IL-18 binding domain, however, no further validation of this sequence was described.
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