Trans-Ancestral Exclusion Mapping of IKZF3 using the SLE ImmunoChip Data We replicated the association signal at IKZF3 in a EA (European-American) SLE ImmunoChip cohort (n cases = 6748, n controls = 11,516), with a total of 93 tag-SNPs in LD with rs2941509 (OR rs2941509 = 1.27, CI 1.14–1.41) showing highly significant association ( Table A4 ).
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Trans-Ancestral Fine-Mapping and Epigenetic Annotation as Tools to Delineate Functionally Relevant Risk Alleles at <i>IKZF1</i> and <i>IKZF3</i> in Systemic Lupus Erythematosus.
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