Stimulation of soluble guanylate cyclase exerts antiinflammatory actions in the liver through a VASP/NF-κB/NLRP3 inflammasome circuit.

Proc Natl Acad Sci U S A · 2020 · PMC7668051 · PMID 33106416

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highly significantno p-value reported

A deeper insight into this analysis identified that, in addition to the oxidation–reduction process, inflammation and innate immune response were two of the top differentially regulated processes in the liver of mice with CDAHFD-induced NASH, with an aggregate count of 901 genes listed with a highly significant P value ( Fig. 2 B ).

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