The interactome of multifunctional HAX1 protein suggests its role in the regulation of energy metabolism, de-aggregation, cytoskeleton organization and RNA-processing.

Biosci Rep · 2020 · PMC7670567 · PMID 33146709

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However, mitochondrial proteins represent only 8% in this dataset (not appearing as important in GO analysis) and the most numerous group is represented by cytoskeletal proteins (38%), which include a highly significant cluster of six septins (SEPT 2, 3, 5, 7, 8,11) linked to another cluster of proteins associated with microtubules and cell division, associated with AURKA.

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