Statistical mechanics of chromosomes: in vivo and in silico approaches reveal high-level organization and structure arise exclusively through mechanical feedback between loop extruders and chromatin substrate properties.

Nucleic Acids Res · 2020 · PMC7672462 · PMID 33080019

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an increasing trendno p-value reported

As shown in Figure 10C , the curve obtains an increasing trend from the starting centromere (bead 0) to another centromere (bead 138) and tends to decrease while circling back.

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