Targeted knockdown of Kv1.3 channels in T lymphocytes corrects the disease manifestations associated with systemic lupus erythematosus.

Sci Adv · 2020 · PMC7673800 · PMID 33208373

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Furthermore, there was also an increase in CD45 cells and T lymphocytes in both LN and DN, albeit with a borderline significance for LN, with DN kidneys additionally showing an increase in CD8 + T cells, exhausted CD8 + T cells, B cells, dendritic cells, mast cells, and neutrophils.

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