Comprehensive Proteomic Profiling of Urinary Exosomes and Identification of Potential Non-invasive Early Biomarkers of Alzheimer's Disease in 5XFAD Mouse Model.

Front Genet · 2020 · PMC7674956 · PMID 33250918

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extremely significantno p-value reported

Both at 2 and 6 months, the concentrations of Annexin 2 ( P = 0.00031 and P = 7.1E-05, respectively) and Clusterin ( P = 5.7E-07 and P = 1.7E-06, respectively) from urinary exosomes in the control group were extremely significant higher than that in 5XFAD mice group ( Figures 9B,C ).

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