Because the ROI-based analysis estimates mean values of predefined brain regions, there could be discrepancy in the results between the ROI-based analysis and SBM; specifically, a small region that shows significance in SBM might not be significant in the ROI-based analysis.
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Long-Term Ambient Air Pollution Exposures and Brain Imaging Markers in Korean Adults: The Environmental Pollution-Induced Neurological EFfects (EPINEF) Study.
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