Single-cell multiomic profiling of human lungs reveals cell-type-specific and age-dynamic control of SARS-CoV2 host genes.

Among variants tested for association in GTEx, we observed a highly significant eQTL for TMPRSS2 expression at rs35074065 (p=3.9 × 10 −11 ) as well as more nominal eQTL evidence at rs1557372 (p=2.9 × 10 −5 ) and rs9974995 (p=3.5 × 10 −6 ).

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