To this end, we focused on genes that were (i) significantly associated with high levels of THBD or NCR1 (fold change > 2 or < −2, and Q or P value < 0.05) from Nanostring data, (ii) with highly significant prognostic value (HR < 1 or >1), and (iii) predominantly expressed by DCs and/or NK cells.
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Cellular and gene signatures of tumor-infiltrating dendritic cells and natural-killer cells predict prognosis of neuroblastoma.
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