Early Intracellular Trafficking and Subsequent Activity of Programmed Cell Death in Channel Catfish Macrophages Infected with <i>Edwardsiella ictaluri</i>.

The highly significant and early inhibition of extrinsic initiator caspase-8 at 1 and 3 h PI in the WT-infected cells compared to the lack of inhibition by the T3SS mutant 65ST indicates that the E. ictaluri T3SS acts to repress caspase-8 activity that would be induced by attachment of E. ictaluri to macrophage surface receptors.

also in 132,142 other papers