Five-Year Trends in Potential Drug Interactions with Direct-Acting Oral Anticoagulants in Patients with Atrial Fibrillation: An Australian-Wide Study.

J Clin Med · 2020 · PMC7694473 · PMID 33167560

Europe PMC DOI

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a decreasing trendno p-value reported

Secondly, perhaps due to increasing awareness, the rate of potential drug interactions with DOACs showed a decreasing trend over a five-year period; however, the rate of prescribing SSRIs/SNRIs was relatively high and remained unchanged.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.