Development and Validation of Stability-Indicating HPLC Methods for the Estimation of Lomefloxacin and Balofloxacin Oxidation Process under ACVA, H2O2, or KMnO4 Treatment. Kinetic Evaluation and Identification of Degradation Products by Mass Spectrometry.

Molecules · 2020 · PMC7697971 · PMID 33187198

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highly significantno p-value reported

Kinetic Evaluation The analysis of the plots 1/c = f(t) for both the oxidation of BAL and LOM while using ACVA and H 2 O 2 demonstrated a highly significant correlation which confirmed that the oxidation process followed the kinetics of second order reaction ( Figure 10 , Figure 11 and Figure 12 ).

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Development and Validation of Stability-Indicating HPLC Methods for the Estimation of Lomefloxacin and Balofloxacin Oxidation Process under ACVA, H<sub>2</sub>O<sub>2</sub>, or KMnO<sub>4</sub> Treatment. Kinetic Evaluation and Identification of Degradation Products by Mass Spectrometry.

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