Nicotinamide Prevents Apolipoprotein B-Containing Lipoprotein Oxidation, Inflammation and Atherosclerosis in Apolipoprotein E-Deficient Mice.

Only the relative levels of the Abca1 mRNA were inversely correlated with aortic atherosclerosis ( Abca1 mRNA: Spearman’s r = −0.42, p < 0.05), while relative levels of the Abcg1 mRNA only showed a nonsignificant trend towards an association with the area of atherosclerotic lesions (Spearman’s r = −0.40, p = 0.06) ( Figure S4, panels (b) and (c) ).

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Only the relative thoracoabdominal aortic level of IL-10 showed a marginal trend towards an inverse correlation with atherosclerosis in ApoE-deficient mice (plasma IL-10 level: Spearman’s r = −0.47, p = 0.06) ( Figure S3, panels (b) and (c) ).

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