The development of these probes would be highly significant for determining the expression level of MTH1 in both in vitro and in vivo and thus provide a potential marker for therapeutics that target DNA damage and repair.
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Radiolabeled 6-(2, 3-Dichlorophenyl)-N4-methylpyrimidine-2, 4-diamine (TH287): A Potential Radiotracer for Measuring and Imaging MTH1.
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