In both cases, the effect was highly significant, with a 137% and 138% fold increase in ERK activation upon AMPAR/NMDAR and D1R blockade, respectively, over BDNF alone ( Figures 5C,I ).
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Dopamine D1 and Glutamate Receptors Co-operate With Brain-Derived Neurotrophic Factor (BDNF) and TrkB to Modulate ERK Signaling in Adult Striatal Slices.
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