highly significantp<0.001
The difference in survival is statistically highly significant (p<0.001) and mortality remains elevated in the tumour-group after five (46.1%, CI: 37.4–54.8% versus 19.0%, CI 11.9–26.2%) and ten years (63.1%, CI: 52.8–73.4% versus 46.6%, CI: 34.1–59.1%) ( Fig 4 ).